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Target
Lysosomal alpha-glucosidase
Ligand
BDBM50283600
Substrate
n/a
Meas. Tech.
ChEMBL_215887 (CHEMBL820819)
IC50
>300000±n/a nM
Citation
 Uchida, C; Kimura, H; Ogawa, S Potent glycosidase inhibitors, N-phenyl cyclic isourea derivatives of 5-amino- and 5-amino-1-C-(hydroxymethyl)-cyclopentane-1,2,3,4-tetraols Bioorg Med Chem Lett 4:2643-2648 (1994)    Article 
Target
Name:
Lysosomal alpha-glucosidase
Synonyms:
Alpha-glucosidase | GAA | LYAG_BOVIN
Type:
PROTEIN
Mol. Mass.:
104738.88
Organism:
Bos taurus
Description:
ChEMBL_215887
Residue:
937
Sequence:
MMRWPPCSRPLLGVCTLLSLALLGHILLHDLEVVPRELRGFSQDEIHQACQPGASSPECRGSPRAAPTQCDLPPNSRFDCAPDKGITPQQCEARGCCYMPAEWPPDAQMGQPWCFFPPSYPSYRLENLTTTETGYTATLTRAVPTFFPKDIMTLRLDMLMETESRLHFTIKDPANRRYEVPLETPRVYSQAPFTLYSVEFSEEPFGVVVRRKLDGRVLLNTTVAPLFFADQFLQLSTSLPSQHITGLAEHLGSLMLSTNWTKITLWNRDIAPEPNVNLYGSHPFYLVLEDGGLAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSTSAITRQVVENMTRAYFPLDVQWNDLDYMDARRDFTFNKDHFGDFPAMVQELHQGGRRYIMIVDPAISSSGPAGTYRPYDEGLRRGVFITNETGQPLIGQVWPGLTAFPDFTNPETLDWWQDMVTEFHAQVPFDGMWIDMNEPSNFVRGSVDGCPDNSLENPPYLPGVVGGTLRAATICASSHQFLSTHYDLHNLYGLTEALASHRALVKARGMRPFVISRSTFAGHGRYSGHWTGDVWSNWEQLSYSVPEILLFNLLGVPLVGADICGFLGNTSEELCVRWTQLGAFYPFMRNHNALNSQPQEPYRFSETAQQAMRKAFTLRYVLLPYLYTLFHRAHVRGETVARPLFLEFPEDPSTWTVDRQLLWGEALLITPVLEAEKVEVTGYFPQGTWYDLQTVPMEAFGSLPPPAPLTSVIHSKGQWVTLSAPLDTINVHLRAGHIIPMQGPALTTTESRKQHMALAVALTASGEAQGELFWDDGESLGVLDGGDYTQLIFLAKNNTFVNKLVHVSSEGASLQLRNVTVLGVATAPQQVLCNSVPVSNFTFSPDTETLAIPVSLTMGEQFVISWS
  
Inhibitor
Name:
BDBM50283600
Synonyms:
5-Amino-cyclopentane-1,2,3,4-tetraol | CHEMBL87120
Type:
Small organic molecule
Emp. Form.:
C5H11NO4
Mol. Mass.:
149.1451
SMILES:
NC1C(O)C(O)C(O)C1O
Structure:
Search PDB for entries with ligand similarity: