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Target
Kappa-type opioid receptor
Ligand
BDBM50366354
Substrate
n/a
Meas. Tech.
ChEBML_92409
Ki
20±n/a nM
Citation
 Gottschlich, R; Ackermann, K; Barber, A; Bartoszyk, G; Greiner, H EMD 61 753 as a favourable representative of structurally novel arylacetamido-type K opiate receptor agonists Bioorg Med Chem Lett 4:677-682 (1994)    Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50366354
Synonyms:
CHEMBL553084
Type:
Small organic molecule
Emp. Form.:
C29H34N2O2
Mol. Mass.:
442.5925
SMILES:
CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(c1ccc(C)cc1)c1ccc(C)cc1 |r|
Structure:
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