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Target
Mu-type opioid receptor
Ligand
BDBM50366357
Substrate
n/a
Meas. Tech.
ChEBML_138891
Ki
>100±n/a nM
Citation
 Gottschlich, R; Ackermann, K; Barber, A; Bartoszyk, G; Greiner, H EMD 61 753 as a favourable representative of structurally novel arylacetamido-type K opiate receptor agonists Bioorg Med Chem Lett 4:677-682 (1994)    Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50366357
Synonyms:
CHEMBL542036
Type:
Small organic molecule
Emp. Form.:
C27H28F2N2O2
Mol. Mass.:
450.5202
SMILES:
CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(c1ccc(F)cc1)c1ccc(F)cc1 |r|
Structure:
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