Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50288199
Substrate
n/a
Meas. Tech.
ChEBML_157564
Ki
5±n/a nM
Citation
 Abbenante, G; Bergman, D; Brinkworth, R; March, D; Reid, R; Hunt, P; James, I; Dancer, R; Garnham, B; Stoermer, M; Fairlie, D Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease Bioorg Med Chem Lett 6:2531-2536 (1996)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50288199
Synonyms:
1-[2-((S)-8-Carbamoylmethyl-6,9-dioxo-2-oxa-7,10-diaza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-trien-11-yl)-2-hydroxy-ethyl]-piperidine-2-carboxylic acid tert-butylamide | CHEMBL84650
Type:
Small organic molecule
Emp. Form.:
C28H43N5O6
Mol. Mass.:
545.6709
SMILES:
CC(C)(C)NC(=O)[C@@H]1CCCCN1C[C@@H](O)[C@H]1Cc2ccc(OCCCC(=O)NC(CC(N)=O)C(=O)N1)cc2
Structure:
Search PDB for entries with ligand similarity: