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Target
Group IID secretory phospholipase A2
Ligand
BDBM50289470
Substrate
n/a
Meas. Tech.
ChEBML_199689
IC50
4500±n/a nM
Citation
 Garigipati, RS; Seibel, G; Mayer, RJ; Bolognese, B; McCord, M; Marshall, LA; Adams, JL Novel frameworks for trifluoromethyl ketone and phosphonate tsa inhibitors of type II PLA2 Bioorg Med Chem Lett 7:1421-1426 (1997)    Article 
Target
Name:
Group IID secretory phospholipase A2
Synonyms:
PA2GD_HUMAN | PLA2G2D | SPLASH
Type:
PROTEIN
Mol. Mass.:
16554.64
Organism:
Homo sapiens (Human)
Description:
ChEMBL_199689
Residue:
145
Sequence:
MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDATDWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLKRNLDTYQKRLRFYWRPHCRGQTPGC
  
Inhibitor
Name:
BDBM50289470
Synonyms:
(E)-3-[4-Benzyloxy-2-(decyloxy-hydroxy-phosphoryl)-phenyl]-acrylic acid | CHEMBL280817
Type:
Small organic molecule
Emp. Form.:
C26H35O6P
Mol. Mass.:
474.5263
SMILES:
CCCCCCCCCCOP(O)(=O)c1cc(OCc2ccccc2)ccc1\C=C\C(O)=O
Structure:
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