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Target
D(2) dopamine receptor
Ligand
BDBM50071217
Substrate
n/a
Meas. Tech.
ChEBML_59914
IC50
81±n/a nM
Citation
 Arlt, M; Böttcher, H; Riethmüller, A; Schneider, G; Bartoszyk, GD; Greiner, H; Seyfried, CA SAR of novel biarylmethylamine dopamine D4 receptor ligands. Bioorg Med Chem Lett 8:2033-8 (1999) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50071217
Synonyms:
2-[4-(3'-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-pyrimidine | CHEMBL62829
Type:
Small organic molecule
Emp. Form.:
C21H21FN4
Mol. Mass.:
348.4166
SMILES:
Fc1cccc(c1)-c1cccc(CN2CCN(CC2)c2ncccn2)c1
Structure:
Search PDB for entries with ligand similarity: