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TargetMatrix metalloproteinase 9
LigandBDBM8465
Substrate/Competitorn/a
Meas. Tech.ChEMBL_102118
IC50 10±n/a nM
Citation Hanessian, SBouzbouz, SBoudon, ATucker, GCPeyroulan, D Picking the S1, S1' and S2' pockets of matrix metalloproteinases. A niche for potent acyclic sulfonamide inhibitors. Bioorg Med Chem Lett9:1691-6 (1999) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Matrix metalloproteinase 9
Name:Matrix metalloproteinase 9
Synonyms:92 kDa gelatinase | 92 kDa type IV collagenase | GELB | Gelatinase B | MMP-9 | Matrix metalloproteinase-9
Type:PROTEIN
Mol. Mass.:80529.41
Organism:Mus musculus
Description:ChEMBL_71659
Residue:730
Sequence:
MSPWQPLLLALLAFGCSSAAPYQRQPTFVVFPKDLKTSNLTDTQLAEAYLYRYGYTRAAQ
MMGEKQSLRPALLMLQKQLSLPQTGELDSQTLKAIRTPRCGVPDVGRFQTFKGLKWDHHN
ITYWIQNYSEDLPRDMIDDAFARAFAVWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYP
FDGKDGLLAHAFPPGAGVQGDAHFDDDELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRS
YSACTTDGRNDGTPWCSTTADYDKDGKFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYS
ACTTKGRSDGYRWCATTANYDQDKLYGFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSS
CTSDGRRDGRLWCATTSNFDTDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMY
PLYSYLEGFPLNKDDIDGIQYLYGRGSKPDPRPPATTTTEPQPTAPPTMCPTIPPTAYPT
VGPTVGPTGAPSPGPTSSPSPGPTGAPSPGPTAPPTAGSSEASTESLSPADNPCNVDVFD
AIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTARTWPALPATLDSAFEDPQTKRVFFF
SGRQMWVYTGKTVLGPRSLDKLGLGPEVTHVSGLLPRRLGKALLFSKGRVWRFDLKSQKV
DPQSVIRVDKEFSGVPWNSHDIFQYQDKAYFCHGKFFWRVSFQNEVNKVDHEVNQVDDVG
YVTYDLLQCP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM8465
n/a
NameBDBM8465
Synonyms:(2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide | BMCL16311 Compound 1a | CGS 27023 | CGS 27023A | CHEMBL514138 | hydroxamate analogue 1
TypeSmall organic molecule
Emp. Form.C18H23N3O5S
Mol. Mass.393.457
SMILESCOc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r|
Structure
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