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Target
D(2) dopamine receptor
Ligand
BDBM50082320
Substrate
n/a
Meas. Tech.
ChEBML_58552
IC50
2680±n/a nM
Citation
 Annoura, H; Nakanishi, K; Uesugi, M; Fukunaga, A; Miyajima, A; Tamura-Horikawa, Y; Tamura, S A novel class of Na+ and Ca2+ channel dual blockers with highly potent anti-ischemic effects. Bioorg Med Chem Lett 9:2999-3002 (1999) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50082320
Synonyms:
4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperidine; hydrochloride | CHEMBL545036
Type:
Small organic molecule
Emp. Form.:
C26H27NO
Mol. Mass.:
369.4987
SMILES:
C(\C=C\c1ccccc1)N1CCC(CC1)c1ccc(Oc2ccccc2)cc1
Structure:
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