Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50451007
Substrate
n/a
Meas. Tech.
ChEBML_29593
EC50
1.1±n/a nM
Citation
 Hutchinson, SA; Baker, SP; Scammells, PJ Adenosine receptor ligands with oxygenated N6-substituents. Bioorg Med Chem Lett 9:933-6 (1999) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50451007
Synonyms:
CHEMBL2112106
Type:
Small organic molecule
Emp. Form.:
C17H21N5O5
Mol. Mass.:
375.3791
SMILES:
[H][C@@]12O[C@]1([H])C1CC2CC1Nc1ncnc2n(cnc12)[C@H]1O[C@H](CO)[C@H](O)[C@@H]1O |r,TLB:10:9:3.1:6,2:3:6:9.8,2:1:6:9.8|
Structure:
Search PDB for entries with ligand similarity: