Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50366627
Substrate
n/a
Meas. Tech.
ChEBML_29593
EC50
2.7±n/a nM
Citation
 Hutchinson, SA; Baker, SP; Scammells, PJ Adenosine receptor ligands with oxygenated N6-substituents. Bioorg Med Chem Lett 9:933-6 (1999) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50366627
Synonyms:
CHEMBL3144087 | CHEMBL608223
Type:
Small organic molecule
Emp. Form.:
C18H23N5O5
Mol. Mass.:
389.4057
SMILES:
OC[C@H]1O[C@@H](Cn2cnc3c(NC4CC5CC4C(=O)C5)ncnc23)[C@H](O)[C@@H]1O |r,TLB:18:17:15:12.13,THB:11:12:15:17.19|
Structure:
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