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Target
Beta-lactamase
Ligand
BDBM50092271
Substrate
n/a
Meas. Tech.
ChEBML_41358
IC50
>700000±n/a nM
Citation
 Grant, EB; Guiadeen, D; Baum, EZ; Foleno, BD; Jin, H; Montenegro, DA; Nelson, EA; Bush, K; Hlasta, DJ The synthesis and SAR of rhodanines as novel class C beta-lactamase inhibitors. Bioorg Med Chem Lett 10:2179-82 (2001) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase TEM
Type:
PROTEIN
Mol. Mass.:
31512.33
Organism:
Enterobacter cloacae
Description:
ChEMBL_41358
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM50092271
Synonyms:
(Z)-5-Benzylidene-2-thioxothiazolidin-4-one | (Z)-5-phenyl-2-thioxothiazolidin-4-one | 5-[1-Phenyl-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one | 5-benzylidene-2-thioxothiazolidin-4-one | CHEMBL305763
Type:
Small organic molecule
Emp. Form.:
C10H7NOS2
Mol. Mass.:
221.299
SMILES:
SC1=NC(=O)C(S1)=Cc1ccccc1 |w:7.8,t:1|
Structure:
Search PDB for entries with ligand similarity: