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Target
Kappa-type opioid receptor
Ligand
BDBM50093784
Substrate
n/a
Meas. Tech.
ChEBML_145823
Ki
1115±n/a nM
Citation
 Coop, A; Jacobson, AE; Aceto, MD; Harris, LS; Traynor, JR; Woods, JH; Rice, KC N-Cyclohexylethyl-N-noroxymorphindole: a mu-opioid preferring analogue of naltrindole. Bioorg Med Chem Lett 10:2449-51 (2001) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42692.90
Organism:
Rattus norvegicus (rat)
Description:
P34975
Residue:
380
Sequence:
MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV
  
Inhibitor
Name:
BDBM50093784
Synonyms:
CHEMBL79443 | [1,5-3H]-17-Cyclohexylmethyl-6,7-dehydro-4,5a -epoxy-3,14-dihydroxy-6,7-2,3-indolo-morphinan
Type:
Small organic molecule
Emp. Form.:
C29H32N2O3
Mol. Mass.:
456.576
SMILES:
Oc1ccc2C[C@H]3N(CC4CCCCC4)CCC45C(Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O |THB:8:7:32:21.4.5|
Structure:
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