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Target
B2 bradykinin receptor
Ligand
BDBM50097733
Substrate
n/a
Meas. Tech.
ChEBML_40436
IC50
>100000±n/a nM
Citation
 Dziadulewicz, EK; Walpole, CS; Snell, CR; Wrigglesworth, R; Hughes, GA; Beattie, D; Wood, JN; Beech, MM; Coote, PR Design of non-peptide CCK2 and NK1 peptidomimetics using 1-(2-nitrophenyl)thiosemicarbazide as a novel common scaffold. Bioorg Med Chem Lett 11:705-9 (2001) [PubMed]  Article 
Target
Name:
B2 bradykinin receptor
Synonyms:
B2 BRADYKININ | B2 bradykinin receptor | B2R | BK-2 receptor | BKRB2_RAT | Bdkrb2 | Bradykinin B2 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44941.22
Organism:
RAT
Description:
B2 BRADYKININ BDKRB2 RAT::P25023
Residue:
396
Sequence:
MDTRSSLCPKTQAVVAVFWGPGCHLSTCIEMFNITTQALGSAHNGTFSEVNCPDTEWWSWLNAIQAPFLWVLFLLAALENIFVLSVFCLHKTNCTVAEIYLGNLAAADLILACGLPFWAITIANNFDWLFGEVLCRVVNTMIYMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWSCTLLLSSPMLVFRTMKDYREEGHNVTACVIVYPSRSWEVFTNMLLNLVGFLLPLSIITFCTVRIMQVLRNNEMKKFKEVQTEKKATVLVLAVLGLFVLCWFPFQISTFLDTLLRLGVLSGCWNERAVDIVTQISSYVAYSNSCLNPLVYVIVGKRFRKKSREVYQAICRKGGCMGESVQMENSMGTLRTSISVDRQIHKLQDWAGNKQ
  
Inhibitor
Name:
BDBM50097733
Synonyms:
(S)-1-[N'-(2-Nitro-phenyl)-hydrazinothiocarbonyl]-pyrrolidine-2-carboxylic acid benzhydryl-amide | CHEMBL164361 | CHEMBL351387
Type:
Small organic molecule
Emp. Form.:
C25H25N5O3S
Mol. Mass.:
475.563
SMILES:
[O-][N+](=O)c1ccccc1N[N-]C(=[SH+])N1CCCC1C(=O)NC(c1ccccc1)c1ccccc1
Structure:
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