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Target
D(1A) dopamine receptor
Ligand
BDBM50109944
Substrate
n/a
Meas. Tech.
ChEBML_60335
Ki
15000±n/a nM
Citation
 Löber, S; Aboul-Fadl, T; Hübner, H; Gmeiner, P Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. Bioorg Med Chem Lett 12:633-6 (2002) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
D(1A) dopamine receptor | D1AR | DOPAMINE D1 | DRD1 | DRD1_BOVIN | Dopamine receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49330.65
Organism:
BOVINE
Description:
DOPAMINE D1 DRD1 BOVINE::Q95136
Residue:
446
Sequence:
MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50109944
Synonyms:
3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-ethynyl-2-methyl-pyrazolo[1,5-a]pyridine | CHEMBL156851
Type:
Small organic molecule
Emp. Form.:
C21H21ClN4
Mol. Mass.:
364.871
SMILES:
Cc1nn2c(cccc2c1CN1CCN(CC1)c1ccc(Cl)cc1)C#C
Structure:
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