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Target
D(3) dopamine receptor
Ligand
BDBM50109952
Substrate
n/a
Meas. Tech.
ChEBML_62138
Ki
4600±n/a nM
Citation
 Löber, S; Aboul-Fadl, T; Hübner, H; Gmeiner, P Di- and trisubstituted pyrazolo[1,5-a]pyridine derivatives: synthesis, dopamine receptor binding and ligand efficacy. Bioorg Med Chem Lett 12:633-6 (2002) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50109952
Synonyms:
3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-7-ethynyl-pyrazolo[1,5-a]pyridine | 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-7-ethynyl-pyrazolo[1,5-a]pyridine | 4-(4-Chloro-phenyl)-1-(7-ethynyl-pyrazolo[1,5-a]pyridin-3-ylmethyl)-piperazin-1-ium | CHEMBL160952
Type:
Small organic molecule
Emp. Form.:
C20H19ClN4
Mol. Mass.:
350.845
SMILES:
Clc1ccc(cc1)N1CCN(Cc2cnn3c(cccc23)C#C)CC1
Structure:
Search PDB for entries with ligand similarity: