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Target
Serine protease 1
Ligand
BDBM50111103
Substrate
n/a
Meas. Tech.
ChEBML_212195
Ki
0.800000±n/a nM
Citation
 Lee, K; Jung, WH; Park, CW; Park, HD; Lee, SH; Kwon, OH Noncovalent tripeptidic thrombin inhibitors incorporating amidrazone, amine and amidine functions at P1. Bioorg Med Chem Lett 12:1017-22 (2002) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50111103
Synonyms:
(S)-1-[(R)-3-(3,4-Dichloro-phenyl)-2-methanesulfonylamino-propionyl]-pyrrolidine-2-carboxylic acid 4-carbamimidoyl-benzylamide | CHEMBL268640
Type:
Small organic molecule
Emp. Form.:
C23H27Cl2N5O4S
Mol. Mass.:
540.463
SMILES:
CS(=O)(=O)N[C@H](Cc1ccc(Cl)c(Cl)c1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N
Structure:
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