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Target
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Ligand
BDBM50366830
Substrate
n/a
Meas. Tech.
ChEBML_32967
Ki
140000±n/a nM
Citation
 Skropeta, D; Schwörer, R; Schmidt, RR Stereoselective synthesis of phosphoramidate alpha(2-6)sialyltransferase transition-state analogue inhibitors. Bioorg Med Chem Lett 13:3351-4 (2003) [PubMed]  Article 
Target
Name:
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
Synonyms:
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase III | GalNAc alpha-2,6-sialyltransferase III | SIA7C_RAT | ST6GalNAc III | STY | Sialyltransferase 7C | Siat7c | St6galnac3
Type:
PROTEIN
Mol. Mass.:
35161.31
Organism:
Rattus norvegicus
Description:
ChEMBL_32967
Residue:
305
Sequence:
MACILKRKPALAVSFIALCILLLAMRLANDVTFPLLLNCFGQPKTKWIPLSYTLRQPLQTHYGYINVRTQEPLQLNCNHCAVVSNSGQMVGQKVGEEIDRASCIWRMNNAPTKGFEEDVGYMTMVRVVSHTSVPLLLKNPDYFFKEASTTIYVIWGPFRNMRKDGNGIVYNMLKKTVDAYPDAQIYVTTEQRMTYCDGVFKDETGKDRVQSGSYLSTGWFTFILAMDACYSIHVYGMINETYCTTEGYRKVPYHYYEQGKDECNEYLLHEHAPYGGHRFITEKKVFAKWAKKHRIVFTHPNWTVS
  
Inhibitor
Name:
BDBM50366830
Synonyms:
CHEMBL611276
Type:
Small organic molecule
Emp. Form.:
C16H19N4O10P2
Mol. Mass.:
489.292
SMILES:
Nc1ccn(C2O[C@H](COP([O-])(=O)N[C@H](c3ccccc3)P([O-])([O-])=O)[C@@H](O)[C@H]2O)c(=O)n1 |r|
Structure:
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