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Target
Carbonic anhydrase 4
Ligand
BDBM50125192
Substrate
n/a
Meas. Tech.
ChEBML_45423
Ki
438±n/a nM
Citation
 Vullo, D; Franchi, M; Gallori, E; Pastorek, J; Scozzafava, A; Pastorekova, S; Supuran, CT Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides. Bioorg Med Chem Lett 13:1005-9 (2003) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4
Type:
Enzyme
Mol. Mass.:
35152.74
Organism:
Bos taurus (bovine)
Description:
Bovine isozyme, isolated from lung microsomes
Residue:
312
Sequence:
MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAKTQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSRAMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQPLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQKPIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLAPVLACLTVGFLR
  
Inhibitor
Name:
BDBM50125192
Synonyms:
CHEMBL6648 | Naphthalene-1-sulfonic acid amide | naphthalene-1-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C10H9NO2S
Mol. Mass.:
207.249
SMILES:
NS(=O)(=O)c1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: