Reaction Details Report a problem with these data
Target
Glutathione hydrolase 1 proenzyme
Ligand
BDBM50148335
Substrate
n/a
Meas. Tech.
ChEBML_68880
pH
8±n/a
Ki
53000±n/a nM
Comments
extracted
Citation
 Lherbet, C; Gravel, C; Keillor, JW Synthesis of S-alkyl L-homocysteine analogues of glutathione and their kinetic studies with gamma-glutamyl transpeptidase. Bioorg Med Chem Lett 14:3451-5 (2004) [PubMed]  Article 
Target
Name:
Glutathione hydrolase 1 proenzyme
Synonyms:
GGT1_RAT | Gamma-glutamyltranspeptidase 1 | Ggt | Ggt1
Type:
PROTEIN
Mol. Mass.:
61615.37
Organism:
Rattus norvegicus
Description:
ChEMBL_68879
Residue:
568
Sequence:
MKNRFLVLGLVAVVLVFVIIGLCIWLPTTSGKPDHVYSRAAVATDAKRCSEIGRDMLQEGGSVVDAAIASLLCMGLINAHSMGIGGGLFFTIYNSTTRKAEVINAREMAPRLANTSMFNNSKDSEEGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARHGFPVGKGLARALDKKRDIIEKTPALCEVFCRQGKVLQEGETVTMPKLADTLQILAQEGARAFYNGSLTAQIVKDIQEAGGIMTVEDLNNYRAEVIEHPMSIGLGDSTLYVPSAPLSGPVLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRFAYAKRTMLGDPKFVDVSQVIRNMSSEFYATQLRARITDETTHPTAYYEPEFYLPDDGGTAHLSVVSEDGSAVAATSTINLYFGSKVLSRVSGILFNDEMDDFSSPNFTNQFGVAPSPANFIKPGKQPLSSMCPSIIVDKDGKVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKNIDQVVTAGLKTRHHHTEVTPDFIAVVQAVVRTSGGWAAASDSRKGGEPAGY
  
Inhibitor
Name:
BDBM50148335
Synonyms:
1-Carboxy-3-[2-(carboxymethyl-carbamoyl)-ethanesulfinyl]-propyl-ammonium; chloride | CHEMBL116299
Type:
Small organic molecule
Emp. Form.:
C9H17N2O6S
Mol. Mass.:
281.306
SMILES:
[NH3+]C(CCS(=O)CCC(=O)NCC(O)=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: