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Target
Adenosine receptor A1
Ligand
BDBM50452003
Substrate
n/a
Meas. Tech.
ChEMBL_29574 (CHEMBL640040)
Ki
354±n/a nM
Citation
 Morrison, CF; Elzein, E; Jiang, B; Ibrahim, PN; Marquart, T; Palle, V; Shenk, KD; Varkhedkar, V; Maa, T; Wu, L; Wu, Y; Zeng, D; Fong, I; Lustig, D; Leung, K; Zablocki, JA Structure-affinity relationships of 5'-aromatic ethers and 5'-aromatic sulfides as partial A1 adenosine agonists, potential supraventricular anti-arrhythmic agents. Bioorg Med Chem Lett 14:3793-7 (2004) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor | AA1R_CAVPO | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor | Adenosine Receptor A1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36501.39
Organism:
GUINEA PIG
Description:
ADENOSINE A1 ADORA1 GUINEA PIG::P47745
Residue:
326
Sequence:
MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPEPPIDEDLPEEKVDD
  
Inhibitor
Name:
BDBM50452003
Synonyms:
CHEMBL609532
Type:
Small organic molecule
Emp. Form.:
C23H26N6O4S2
Mol. Mass.:
514.62
SMILES:
COc1ccc2sc(SC[C@H]3OC([C@H](O)[C@@H]3O)n3cnc4c(NC5CCCC5)ncnc34)nc2c1 |r|
Structure:
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