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Target
Carbonic anhydrase 4
Ligand
BDBM50141773
Substrate
n/a
Meas. Tech.
ChEBML_45430
Ki
92±n/a nM
Citation
 Pastorekova, S; Casini, A; Scozzafava, A; Vullo, D; Pastorek, J; Supuran, CT Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX. Bioorg Med Chem Lett 14:869-73 (2004) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4
Type:
Enzyme
Mol. Mass.:
35152.74
Organism:
Bos taurus (bovine)
Description:
Bovine isozyme, isolated from lung microsomes
Residue:
312
Sequence:
MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAKTQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSRAMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQPLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQKPIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLAPVLACLTVGFLR
  
Inhibitor
Name:
BDBM50141773
Synonyms:
2,4,6-Trimethyl-1-(4-sulfamoyl-benzyl)-pyridinium; perchlorate | CHEMBL170938
Type:
Small organic molecule
Emp. Form.:
C15H19N2O2S
Mol. Mass.:
291.388
SMILES:
Cc1cc(C)[n+](Cc2ccc(cc2)S(N)(=O)=O)c(C)c1
Structure:
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