Reaction Details Report a problem with these data
Target
S-adenosylmethionine decarboxylase proenzyme
Ligand
BDBM50367079
Substrate
n/a
Meas. Tech.
ChEMBL_197049 (CHEMBL806288)
Ki
540000±n/a nM
Citation
 Kolb, M; Danzin, C; Barth, J; Claverie, N Synthesis and biochemical properties of chemically stable product analogues of the reaction catalyzed by S-adenosyl-L-methionine decarboxylase. J Med Chem 25:550-6 (1982) [PubMed]  Article 
Target
Name:
S-adenosylmethionine decarboxylase proenzyme
Synonyms:
Amd1 | DCAM_RAT | S-adenosylmethionine decarboxylase 1
Type:
PROTEIN
Mol. Mass.:
38134.93
Organism:
Rattus norvegicus
Description:
ChEMBL_197052
Residue:
333
Sequence:
MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDLPESRVINQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQS
  
Inhibitor
Name:
BDBM50367079
Synonyms:
CHEMBL610141
Type:
Small organic molecule
Emp. Form.:
C12H19N7O3
Mol. Mass.:
309.3244
SMILES:
NCCNC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure:
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