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Target
Alpha-2A adrenergic receptor
Ligand
BDBM50027034
Substrate
n/a
Meas. Tech.
ChEBML_33034
Ki
1.8±n/a nM
Citation
 Saari, WS; Halczenko, W; Randall, WC; Lotti, VJ alpha-Adrenergic activities of some substituted 2-(aminomethyl)imidazolines. J Med Chem 26:1769-72 (1984) [PubMed]  Article 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
ADA2A_BOVIN | ADRA2A | Alpha-2A adrenergic receptor | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | Alpha-2D adrenergic receptor | Alpha-2Da adrenergic receptor | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha2A | adrenergic Alpha2D
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49275.13
Organism:
BOVINE
Description:
adrenergic Alpha2 0 BOVINE::Q28838
Residue:
452
Sequence:
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSGQPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATAAELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGAGADALDLEESSSSEHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM50027034
Synonyms:
(4,5-Dihydro-1H-imidazol-2-ylmethyl)-phenyl-p-tolyl-amine | CHEMBL51131
Type:
Small organic molecule
Emp. Form.:
C17H19N3
Mol. Mass.:
265.3529
SMILES:
Cc1ccc(cc1)N(CC1=NCCN1)c1ccccc1 |t:10|
Structure:
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