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Target
Histamine H2 receptor
Ligand
BDBM50026287
Substrate
n/a
Meas. Tech.
ChEBML_85684
IC50
1000000±n/a nM
Citation
 Martinez, J; Bali, JP; Magous, R; Laur, J; Lignon, MF; Briet, C; Nisato, D; Castro, B Structure-activity relationships of C-terminal tri- and tetrapeptide fragments that inhibit gastrin activity. J Med Chem 28:273-8 (1985) [PubMed]  Article 
Target
Name:
Histamine H2 receptor
Synonyms:
Gastric receptor I | H2R | HISTAMINE H2 | HRH2_RAT | Hrh2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40269.37
Organism:
RAT
Description:
HISTAMINE H2 HRH2 RAT::P25102
Residue:
358
Sequence:
MEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQLFHCKFASHNSHKTSLRLNNSLLPRSQSREGRWQEEKPLKLQVWSGTELTHPQGNPIR
  
Inhibitor
Name:
BDBM50026287
Synonyms:
3-{2-[2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionylamino]-acetylamino}-succinamic acid | CHEMBL328055
Type:
Small organic molecule
Emp. Form.:
C22H29N5O7
Mol. Mass.:
475.495
SMILES:
CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(N)=O
Structure:
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