Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50021572
Substrate
n/a
Meas. Tech.
ChEMBL_151705 (CHEMBL760454)
IC50
0.000±n/a nM
Comments
0.0000700 20220120
Citation
 Ponpipom, MM; Bugianesi, RL; Brooker, DR; Yue, BZ; Hwang, SB; Shen, TY Structure-activity relationships of kadsurenone analogues. J Med Chem 30:136-42 (1987) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50021572
Synonyms:
(2S,3S)-2-(3,4-Dimethoxy-phenyl)-3-methyl-5-propyl-2,3-dihydro-benzofuran-6-ol | CHEMBL287709
Type:
Small organic molecule
Emp. Form.:
C20H24O4
Mol. Mass.:
328.4022
SMILES:
CCCc1cc2[C@H](C)[C@H](Oc2cc1O)c1ccc(OC)c(OC)c1
Structure:
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