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Target
Mu-type opioid receptor
Ligand
BDBM50016458
Substrate
n/a
Meas. Tech.
ChEMBL_145157 (CHEMBL755961)
Ki
53±n/a nM
Citation
 Portoghese, PS; Larson, DL; Ronsisvalle, G; Schiller, PW; Nguyen, TM; Lemieux, C; Takemori, AE Hybrid bivalent ligands with opiate and enkephalin pharmacophores. J Med Chem 30:1991-4 (1987) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50016458
Synonyms:
2-{2-[2-(2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-4-{[(carbamoylmethyl-carbamoyl)-methyl]-carbamoyl}-butyrylamino)-acetylamino]-3-phenyl-propionylamino}-4-methyl-pentanoic acid | CHEMBL60377
Type:
Small organic molecule
Emp. Form.:
C35H48N8O10
Mol. Mass.:
740.8032
SMILES:
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@H](CCC(=O)NCC(=O)NCC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O
Structure:
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