Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50367865
Substrate
n/a
Meas. Tech.
ChEBML_28977
Ki
3.7±n/a nM
Citation
 Jacobson, KA; Barone, S; Kammula, U; Stiles, GL Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors. J Med Chem 32:1043-51 (1989) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50367865
Synonyms:
CHEMBL603937
Type:
Small organic molecule
Emp. Form.:
C36H39N9O6S
Mol. Mass.:
725.817
SMILES:
Cc1ccc(NC(=S)NCCNC(=O)Cc2ccc(NC(=O)Cc3ccc(Nc4ncnc5n(cnc45)C4O[C@H](CO)[C@@H](O)[C@H]4O)cc3)cc2)cc1 |r|
Structure:
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