Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50017029
Substrate
n/a
Meas. Tech.
ChEBML_201888
IC50
7800±n/a nM
Citation
 Gray, NM; Cheng, BK; Mick, SJ; Lair, CM; Contreras, PC Phencyclidine-like effects of tetrahydroisoquinolines and related compounds. J Med Chem 32:1242-8 (1989) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50017029
Synonyms:
2-Benzyl-1,2,3,4-tetrahydro-isoquinoline | CHEMBL21272
Type:
Small organic molecule
Emp. Form.:
C16H17N
Mol. Mass.:
223.3129
SMILES:
C(N1CCc2ccccc2C1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: