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TargetAlcohol dehydrogenase
LigandBDBM50421763
Substrate/Competitorn/a
Meas. Tech.ChEMBL_30986
Kd 27000±n/a nM
Citation Goldstein, BMBell, JEMarquez, VE Dehydrogenase binding by tiazofurin anabolites. J Med Chem33:1123-7 (1990) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alcohol dehydrogenase
Name:Alcohol dehydrogenase
Synonyms:n/a
Type:n/a
Mol. Mass.:n/a
Description:ASSAY_ID of ChEMBL is 30849
Components:This complex has 2 components.
Component 1
Name:Alcohol dehydrogenase E chain
Synonyms:1.1.1.1 | Alcohol dehydrogenase E chain
Type:PROTEIN
Mol. Mass.:39942.66
Organism:Equus caballus
Description:ChEMBL_105061
Residue:375
Sequence:
MSTAGKVIKCKAAVLWEEKKPFSIEEVEVAPPKAHEVRIKMVATGICRSDDHVVSGTLVT
PLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFTPQCGKCRVCKHPEGNFCLKNDLSMP
RGTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLIGCGFSTG
YGSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATE
CVNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVTALSCCQEAYGVSVIVGVPPDSQ
NLSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGF
DLLRSGESIRTILTF
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Component 2
Name:Alcohol dehydrogenase S chain
Synonyms:1.1.1.1 | Alcohol dehydrogenase S chain
Type:PROTEIN
Mol. Mass.:39633.49
Organism:Equus caballus
Description:ChEMBL_105061
Residue:374
Sequence:
MSTAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVA
PLPVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKNLSMPR
GTMQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGY
GSAVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATEC
VNPQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQN
LSMNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFD
LLRSGKSIRTILTF
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  Blast E-value cutoff:
BDBM50421763
NameBDBM50421763
Synonyms:CHEMBL2364562
TypeSmall organic molecule
Emp. Form.C19H25N7O14P2S
Mol. Mass.669.453
SMILESNC(=O)c1csc(n1)[C@H]1O[C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@H](O)[C@@H]1O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a