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Target
D(2) dopamine receptor
Ligand
BDBM50010655
Substrate
n/a
Meas. Tech.
ChEBML_61432
IC50
820±n/a nM
Citation
 Högberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Ström, P; Hall, H; Ogren, SO Potential antipsychotic agents 5. Synthesis and antidopaminergic properties of substituted 5,6-dimethoxysalicylamides and related compounds. J Med Chem 33:1155-63 (1990) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50010655
Synonyms:
(S)-3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,5,6-trimethoxy-benzamide | CHEMBL16252
Type:
Small organic molecule
Emp. Form.:
C19H30N2O4
Mol. Mass.:
350.4525
SMILES:
CCN1CCCC1CNC(=O)c1c(OC)c(CC)cc(OC)c1OC
Structure:
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