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Target
Mu-type opioid receptor
Ligand
BDBM50008853
Substrate
n/a
Meas. Tech.
ChEBML_146264
Ki
170±n/a nM
Citation
 Halfpenny, PR; Horwell, DC; Hughes, J; Humblet, C; Hunter, JC; Neuhaus, D; Rees, DC Highly selective kappa opioid analgesics. 4. Synthesis of some conformationally restricted naphthalene derivatives with high receptor affinity and selectivity. J Med Chem 34:190-4 (1991) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50008853
Synonyms:
2-Bromo-4,5-dihydro-3H-naphtho[1,8-bc]thiophene-5-carboxylic acid methyl-(7-pyrrolidin-1-yl-1-oxa-spiro[4.5]dec-8-yl)-amide; compound with toluene-4-sulfonic acid | CHEMBL300832
Type:
Small organic molecule
Emp. Form.:
C26H33BrN2O2S
Mol. Mass.:
517.521
SMILES:
CN([C@H]1CCC2(CCCO2)C[C@@H]1N1CCCC1)C(=O)C1CCc2c(Br)sc3cccc1c23
Structure:
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