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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50041254
Substrate/Competitorn/a
Meas. Tech.ChEMBL_201271
Ki 61±n/a nM
Citation Glennon, RASmith, JDIsmaiel, AMel-Ashmawy, MBattaglia, GFischer, JB Identification and exploitation of the sigma-opiate pharmacophore. J Med Chem34:1094-8 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma opioid receptor
Synonyms:Aging-associated gene 8 protein | SIG-1R | SR-BP | SR31747-binding protein | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:Enzyme Catalytic Domain
Mol. Mass.:25124.85
Organism:Homo sapiens (Human)
Description:Sigma 0 HUMAN::Q99720
Residue:223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50041254
NameBDBM50041254
Synonyms:((R)-1-Methyl-2-phenyl-ethyl)-phenethyl-amine | CHEMBL278585
TypeSmall organic molecule
Emp. Form.C17H21N
Mol. Mass.239.3553
SMILESC[C@H](Cc1ccccc1)NCCc1ccccc1
Structure
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