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TargetSigma non-opioid intracellular receptor 1
LigandBDBM50006968
Substrate/Competitorn/a
Meas. Tech.ChEMBL_201278
Ki 7.9±n/a nM
Citation Glennon, RAIsmaiel, AMSmith, JDYousif, Mel-Ashmawy, MHerndon, JLFischer, JBHowie, KJServer, AC Binding of substituted and conformationally restricted derivatives of N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane at sigma-receptors. J Med Chem34:1855-9 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sigma non-opioid intracellular receptor 1
Name:Sigma opioid receptor
Synonyms:Aging-associated gene 8 protein | SIG-1R | SR-BP | SR31747-binding protein | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:Enzyme Catalytic Domain
Mol. Mass.:25124.85
Organism:Homo sapiens (Human)
Description:Sigma 0 HUMAN::Q99720
Residue:223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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  Blast E-value cutoff:
BDBM50006968
NameBDBM50006968
Synonyms:(3-Phenyl-propyl)-(6,7,8,9-tetrahydro-5H-benzocyclohepten-7-yl)-amine | CHEMBL296601
TypeSmall organic molecule
Emp. Form.C20H25N
Mol. Mass.279.4192
SMILESC(CNC1CCc2ccccc2CC1)Cc1ccccc1
Structure
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n/a