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Target
Vasopressin V2 receptor
Ligand
BDBM50406623
Substrate
n/a
Meas. Tech.
ChEMBL_214866 (CHEMBL820052)
Kd
100±n/a nM
Citation
 Barbeau, D; Guay, S; Neugebauer, W; Escher, E Preparation and biological activities of potential vasopressin photoaffinity labels. J Med Chem 35:151-7 (1992) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
AVPR2 | V2R_PIG
Type:
PROTEIN
Mol. Mass.:
40556.17
Organism:
Sus scrofa
Description:
ChEMBL_214870
Residue:
370
Sequence:
MLRATTSAVPRALSWPAAPGNGSEREPLDDRDPLLARVELALLSTVFVAVALSNGLVLGALVRRGRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATYRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGDGSGVLDCWASFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHTSLVPGPAERAGGHRGGRRAGSPREGARVSAAMAKTARMTLVIVAVYVLCWAPFFLVQLWSVWDPKAPREGPPFVLLMLLASLNSCTNPWIYASFSSSISSELRSLLCCPRRRTPPSLRPQEESCATASSFSARDTSS
  
Inhibitor
Name:
BDBM50406623
Synonyms:
CHEMBL2115369
Type:
Small organic molecule
Emp. Form.:
C58H79N11O12S2
Mol. Mass.:
1186.444
SMILES:
COc1ccc(C[C@@H]2NC(=O)C3(CCCC3)CSSC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC2=O)C(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)cc1
Structure:
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