Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetAdenosine A1 receptor
LigandBDBM50004578
Substrate/Competitorn/a
Meas. Tech.ChEMBL_29289
Ki 4.4±n/a nM
Citation Shimada, JSuzuki, FNonaka, HIshii, A 8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors. J Med Chem35:924-30 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine A1 receptor
Name:Adenosine A1 receptor
Synonyms:A1 adenosine receptor | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine Receptor A1
Type:Enzyme Catalytic Domain
Mol. Mass.:36501.39
Organism:GUINEA PIG
Description:ADENOSINE A1 ADORA1 GUINEA PIG::P47745
Residue:326
Sequence:
MPHSVSAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIASLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAAVAIAGCWILSLVVGLTPMFGWNNLSKIEMAWAANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLSKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCHKPTILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPEPPIDEDLPEEKVDD
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50004578
NameBDBM50004578
Synonyms:8-Bicyclo[2.2.1]hept-2-yl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | CHEMBL415321
TypeSmall organic molecule
Emp. Form.C18H26N4O2
Mol. Mass.330.4246
SMILESCCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CC2CCC1C2 |TLB:6:17:23:21.20|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a