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Target
D(2) dopamine receptor
Ligand
BDBM50001964
Substrate
n/a
Meas. Tech.
ChEMBL_62419 (CHEMBL674823)
Ki
7730±n/a nM
Citation
 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Dopaminergic and serotonergic activities of imidazoquinolinones and related compounds. J Med Chem 35:1076-92 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50001964
Synonyms:
5-(Bis-cyclopropylmethyl-amino)-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one | CHEMBL273711
Type:
Small organic molecule
Emp. Form.:
C18H23N3O
Mol. Mass.:
297.3947
SMILES:
O=c1[nH]c2cccc3CC(Cn1c23)N(CC1CC1)CC1CC1
Structure:
Search PDB for entries with ligand similarity: