Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50006091
Substrate
n/a
Meas. Tech.
ChEBML_221704
IC50
23100±n/a nM
Citation
 Wissner, A; Carroll, ML; Green, KE; Kerwar, SS; Pickett, WC; Schaub, RE; Torley, LW; Wrenn, S; Kohler, CA Analogues of platelet activating factor. 6. Mono- and bis-aryl phosphate antagonists of platelet activating factor. J Med Chem 35:1650-62 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50006091
Synonyms:
2-{3-[(3-Hexadecyloxy-2-methoxy-propoxy)-hydroxy-phosphoryloxy]-benzyl}-isoquinolinium | CHEMBL296539
Type:
Small organic molecule
Emp. Form.:
C36H54NO6P
Mol. Mass.:
627.7908
SMILES:
CCCCCCCCCCCCCCCCOCC(COP([O-])(=O)Oc1cccc(C[n+]2ccc3ccccc3c2)c1)OC
Structure:
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