Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50006099
Substrate
n/a
Meas. Tech.
ChEBML_221704
IC50
1990±n/a nM
Citation
 Wissner, A; Carroll, ML; Green, KE; Kerwar, SS; Pickett, WC; Schaub, RE; Torley, LW; Wrenn, S; Kohler, CA Analogues of platelet activating factor. 6. Mono- and bis-aryl phosphate antagonists of platelet activating factor. J Med Chem 35:1650-62 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50006099
Synonyms:
1-{3-[Hydroxy-(2-methoxy-3-tetradecyloxy-phenoxy)-phosphoryloxy]-benzyl}-quinolinium | CHEMBL47760
Type:
Small organic molecule
Emp. Form.:
C37H48NO6P
Mol. Mass.:
633.7539
SMILES:
CCCCCCCCCCCCCCOc1cccc(OP([O-])(=O)Oc2cccc(C[n+]3cccc4ccccc34)c2)c1OC
Structure:
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