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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50042469
Substrate
n/a
Meas. Tech.
ChEMBL_98894 (CHEMBL703402)
Ki
71±n/a nM
Citation
 Trybulski, EJ; Zhang, J; Kramss, RH; Mangano, RM The synthesis and biochemical pharmacology of enantiomerically pure methylated oxotremorine derivatives. J Med Chem 36:3533-41 (1994) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51555.53
Organism:
RAT
Description:
P10980
Residue:
466
Sequence:
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50042469
Synonyms:
1-(4-Dimethylamino-but-2-ynyl)-3-methyl-pyrrolidin-2-one | CHEMBL119615
Type:
Small organic molecule
Emp. Form.:
C11H18N2O
Mol. Mass.:
194.2734
SMILES:
C[C@@H]1CCN(CC#CCN(C)C)C1=O
Structure:
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