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Target
D(2) dopamine receptor
Ligand
BDBM50036761
Substrate
n/a
Meas. Tech.
ChEMBL_59887 (CHEMBL673013)
Ki
25±n/a nM
Citation
 Gilligan, PJ; Kergaye, AA; Lewis, BM; McElroy, JF Piperidinyltetralin sigma ligands. J Med Chem 37:364-70 (1994) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50036761
Synonyms:
1'-(2-phenylethyl)-3,4-dihydro-1H-spiro[naphthalene-2,4'-piperidine]-1-one chloride | CHEMBL553311
Type:
Small organic molecule
Emp. Form.:
C24H26FNO2
Mol. Mass.:
379.4671
SMILES:
Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)CCc1ccccc1C2=O
Structure:
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