Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50041378
Substrate
n/a
Meas. Tech.
ChEMBL_61759 (CHEMBL670521)
IC50
>100000±n/a nM
Citation
 Monge, A; Peña, MC; Palop, JA; Calderó, JM; Roca, J; García, E; Romero, G; del Río, J; Lasheras, B Synthesis of 2-piperazinylbenzothiazole and 2-piperazinylbenzoxazole derivatives with 5-HT3 antagonist and 5-HT4 agonist properties. J Med Chem 37:1320-5 (1994) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50041378
Synonyms:
2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-benzooxazole | CHEMBL25396
Type:
Small organic molecule
Emp. Form.:
C18H19N3O2
Mol. Mass.:
309.3624
SMILES:
COc1ccccc1N1CCN(CC1)c1nc2ccccc2o1
Structure:
Search PDB for entries with ligand similarity: