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Target
D(3) dopamine receptor
Ligand
BDBM50035353
Substrate
n/a
Meas. Tech.
ChEMBL_62902 (CHEMBL676141)
Ki
164±n/a nM
Citation
 Ennis, MD; Stjernlöf, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikström, H; Haadsma-Svensson, SR; Lin, CH Structure-activity relationships in the 8-amino-6,7,8,9-tetrahydro-3H-benz[e]indole ring system. 2. Effects of 8-amino nitrogen substitution on serotonin receptor binding and pharmacology. J Med Chem 38:2217-30 (1995) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50035353
Synonyms:
8-(Cyclopropylmethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde | CHEMBL71640
Type:
Small organic molecule
Emp. Form.:
C20H26N2O
Mol. Mass.:
310.4332
SMILES:
CCCN(CC1CC1)C1CCc2ccc3[nH]cc(C=O)c3c2C1
Structure:
Search PDB for entries with ligand similarity: