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Target
D(2) dopamine receptor
Ligand
BDBM50029268
Substrate
n/a
Meas. Tech.
ChEMBL_62394 (CHEMBL672949)
Ki
28±n/a nM
Citation
 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA Piperazinylalkyl heterocycles as potential antipsychotic agents. J Med Chem 38:4198-210 (1995) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50029268
Synonyms:
Azepan-1-yl-{5-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-thiophen-3-yl}-methanone; hydrochloride | CHEMBL544373
Type:
Small organic molecule
Emp. Form.:
C25H35N3O2S
Mol. Mass.:
441.629
SMILES:
CC(C)Oc1ccccc1N1CCN(Cc2cc(cs2)C(=O)N2CCCCCC2)CC1
Structure:
Search PDB for entries with ligand similarity: