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Target
Ornithine decarboxylase
Ligand
BDBM50029359
Substrate
n/a
Meas. Tech.
ChEMBL_148132 (CHEMBL753381)
Ki
720000±n/a nM
Citation
 Aizencang, G; Frydman, RB; Giorgieri, S; Sambrotta, L; Guerra, L; Frydman, B Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase. J Med Chem 38:4337-41 (1995) [PubMed]  Article 
Target
Name:
Ornithine decarboxylase
Synonyms:
DCOR_RAT | Odc | Odc1
Type:
PROTEIN
Mol. Mass.:
51037.04
Organism:
Rattus norvegicus
Description:
ChEMBL_1344641
Residue:
461
Sequence:
MGSFTKEEFDCHILDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDVLKKHLRWLKALPRVTPFYAVKCNDSRAIVSTLAAIGTGFDCASKTEIQLVQGLGVPPERIIYANPCKQVSQIKYAASNGVQMMTFDSEIELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLLLERAKELNIDVIGVSFHVGSGCTDPETFVQAVSDARCVFDMGTEVGFSMYLLDIGGGFPGSEDTKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKTVWKEQTGSDDEDESNEQTLMYYVNDGVYGSFNCILYDHAHVKALLQKRPKPDEKYYSSSIWGPTCDGLDRIVERCSLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPNIYYVMSRSMWQLMKQIQSHGFPPEVEEQDVGTLPMSCAQESGMDRHPAACASASINV
  
Inhibitor
Name:
BDBM50029359
Synonyms:
4-Amino-2-aminomethyl-3-methyl-butyric acid | CHEMBL344906
Type:
Small organic molecule
Emp. Form.:
C6H14N2O2
Mol. Mass.:
146.1876
SMILES:
CC(CN)C(CN)C(O)=O
Structure:
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