Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50048238
Substrate
n/a
Meas. Tech.
ChEMBL_61949 (CHEMBL671349)
Ki
477±n/a nM
Citation
 Thurkauf, A; Yuan, J; Chen, X; Wasley, JW; Meade, R; Woodruff, KH; Huston, K; Ross, PC 1-Phenyl-3-(aminomethyl)pyrroles as potential antipsychotic agents. Synthesis and dopamine receptor binding. J Med Chem 38:4950-2 (1996) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3 | DRD3_CHLAE
Type:
PROTEIN
Mol. Mass.:
44355.59
Organism:
Chlorocebus aethiops
Description:
ChEMBL_105569
Residue:
400
Sequence:
MAPLSQLSGHLNYTCGVENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRVCCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVTLMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDRAHLELKRYYSICQDTALGGPGFQERGGELKREERTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50048238
Synonyms:
4-(4-Chloro-phenyl)-1-(1-phenyl-1H-pyrrol-3-ylmethyl)-piperidin-4-ol | CHEMBL147003
Type:
Small organic molecule
Emp. Form.:
C22H23ClN2O
Mol. Mass.:
366.884
SMILES:
OC1(CCN(Cc2ccn(c2)-c2ccccc2)CC1)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: