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Reaction Details
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TargetLTB4R
LigandBDBM50052025
Substrate/Competitorn/a
Meas. Tech.ChEMBL_99835
Ki 1±n/a nM
Citation Brooks, CDSummers, JB Modulators of leukotriene biosynthesis and receptor activation. J Med Chem39:2629-54 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
LTB4R
Name:LTB4R
Synonyms:Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | LTB4-R 1 | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2Y purinoceptor 7 | P2Y7
Type:Enzyme Catalytic Domain
Mol. Mass.:37582.68
Organism:HUMAN
Description:Leukotriene B4 R1 LTB4R HUMAN::Q15722
Residue:352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50052025
NameBDBM50052025
Synonyms:6-{2-(2-Carboxy-ethyl)-3-[6-(4-oxo-8-propyl-chroman-7-yloxy)-hexyl]-phenoxy}-hexanoic acid | CHEMBL86900 | Ro-25-4094
TypeSmall organic molecule
Emp. Form.C33H44O8
Mol. Mass.568.6977
SMILESCCCc1c(OCCCCCCc2cccc(OCCCCCC(O)=O)c2CCC(O)=O)ccc2C(=O)CCOc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a