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Reaction Details
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TargetLTB4R
LigandBDBM50052021
Substrate/Competitorn/a
Meas. Tech.ChEMBL_99851
IC50 4±n/a nM
Citation Brooks, CDSummers, JB Modulators of leukotriene biosynthesis and receptor activation. J Med Chem39:2629-54 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
LTB4R
Name:Leukotriene B4 receptor
Synonyms:Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | LTB4-R 1 | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2Y purinoceptor 7 | P2Y7
Type:Enzyme Catalytic Domain
Mol. Mass.:37582.68
Organism:Homo sapiens (Human)
Description:Leukotriene B4 R1 LTB4R HUMAN::Q15722
Residue:352
Sequence:
MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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  Blast E-value cutoff:
BDBM50052021
NameBDBM50052021
Synonyms:4-[5-(4-Carbamimidoyl-phenoxy)-pentyloxy]-N,N-diisopropyl-3-methoxy-benzamide | CGS-250190 | CHEMBL89326
TypeSmall organic molecule
Emp. Form.C26H37N3O4
Mol. Mass.455.5897
SMILESCOc1cc(ccc1OCCCCCOc1ccc(cc1)C(N)=N)C(=O)N(C(C)C)C(C)C
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a