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Target
D(1) dopamine receptor
Ligand
BDBM50033116
Substrate
n/a
Meas. Tech.
ChEMBL_59005 (CHEMBL880003)
EC50
8.2±n/a nM
Citation
 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. J Med Chem 40:1585-99 (1997) [PubMed]  Article 
Target
Name:
D(1) dopamine receptor
Synonyms:
D(1) dopamine receptor | DRD1_CARAU | Dopamine D1 receptor
Type:
n/a
Mol. Mass.:
40664.04
Organism:
Carassius auratus
Description:
n/a
Residue:
363
Sequence:
MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRRDLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQIRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSNGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSLNKN
  
Inhibitor
Name:
BDBM50033116
Synonyms:
(1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol | A-77636 | CHEMBL291143 | cid_6603703
Type:
Small organic molecule
Emp. Form.:
C20H27NO3
Mol. Mass.:
329.4333
SMILES:
NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)C12CC3CC(CC(C3)C1)C2 |TLB:21:16:23:22.20.19,21:20:23:15.16.17,THB:19:18:15:22.20.21,19:20:15:23.18.17|
Structure:
Search PDB for entries with ligand similarity: