Reaction Details Report a problem with these data
Target
D(1) dopamine receptor
Ligand
BDBM50057851
Substrate
n/a
Meas. Tech.
ChEMBL_59005 (CHEMBL880003)
EC50
80±n/a nM
Citation
 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Substituted hexahydrobenzo[f]thieno[c]quinolines as dopamine D1-selective agonists: synthesis and biological evaluation in vitro and in vivo. J Med Chem 40:1585-99 (1997) [PubMed]  Article 
Target
Name:
D(1) dopamine receptor
Synonyms:
D(1) dopamine receptor | DRD1_CARAU | Dopamine D1 receptor
Type:
n/a
Mol. Mass.:
40664.04
Organism:
Carassius auratus
Description:
n/a
Residue:
363
Sequence:
MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRRDLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQIRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSNGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSLNKN
  
Inhibitor
Name:
BDBM50057851
Synonyms:
(5aS,11bR)-2-Phenyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol | CHEMBL43514
Type:
Small organic molecule
Emp. Form.:
C21H19NO2S
Mol. Mass.:
349.446
SMILES:
Oc1cc2CC[C@@H]3NCc4sc(cc4[C@H]3c2cc1O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: