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TargetMelanocyte-stimulating hormone receptor
LigandBDBM50454567
Substrate/Competitorn/a
Meas. Tech.ChEMBL_105833
IC50>10000±n/a nM
Citation Haskell-Luevano, CHendrata, SNorth, CSawyer, TKHadley, MEHruby, VJDickinson, CGantz, I Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R. J Med Chem40:2133-9 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melanocyte-stimulating hormone receptor
Name:Melanocortin receptor (M1 and M4)
Synonyms:MC1-R | MSH-R | Melanocortin MC1 | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:Enzyme
Mol. Mass.:34717.23
Organism:Homo sapiens (Human)
Description:Q01726
Residue:317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVV
ATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVI
DVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFI
AYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGA
VTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF
HSQELRRTLKEVLTCSW
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50454567
NameBDBM50454567
Synonyms:CHEMBL2114996
TypeSmall organic molecule
Emp. Form.C34H43N11O5
Mol. Mass.685.7759
SMILESCC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |wU:4.4,14.15,wD:36.38,25.27,(-.04,-6.35,;1.29,-5.57,;1.28,-4.02,;2.63,-6.3,;3.95,-5.53,;3.93,-3.98,;4.32,-2.5,;3.41,-1.27,;4.28,-.01,;5.75,-.48,;5.78,-2,;5.29,-6.28,;5.31,-7.82,;6.61,-5.5,;7.94,-6.23,;7.97,-7.78,;7.19,-9.11,;5.66,-9.11,;4.87,-10.44,;5.64,-11.79,;7.19,-11.79,;7.97,-10.46,;9.26,-5.46,;9.24,-3.92,;10.6,-6.21,;11.91,-5.43,;11.89,-3.9,;13.22,-3.1,;13.21,-1.57,;14.52,-.78,;14.5,.75,;15.83,1.53,;13.16,1.5,;13.27,-6.18,;13.28,-7.71,;14.57,-5.4,;15.92,-6.14,;15.95,-7.68,;15.17,-9.02,;13.62,-9.04,;13.16,-10.51,;14.43,-11.4,;14.61,-12.92,;16.02,-13.51,;17.25,-12.62,;17.06,-11.09,;15.65,-10.47,;17.25,-5.35,;18.58,-6.11,;17.21,-3.81,)|
Structure
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